What makes our food taste so delicious? (audio)

How do microRNAs regulate sleep?

Are there extra dimensions?

How does experience when we are very young influence the way in which our brains are constructed?

Can we make materials that behave like living organisms?

How can we identify each of the animal species on earth (from single cells to blue whales) using the same reagents in a single-tube reaction?

How do neural changes with age affect memory?

How do we see?

Is wave mechanics necessary to understand chemical reactions?

How to make environmentally friendly catalysts?

How do we remember what we see?

How are cell shape and architecture determined?

Why do older adults form more positive first impressions from faces than younger adults do?

How do ion channel proteins choose the right ion that enables them to make electricity in cells?

How does a virus assemble?

How do genes influence behavior?

How is the heart controlled by the brain?

What turns connected neurons into functioning brains?

Why are some roads to infinity better than others in a geodesic metric space?

How do stress-related changes in the endocrine-immune interplay affect health?

How do chromosomes communicate with each other?

How does the brain learn and remember?

How does pond scum float?

How can science be conveyed in a fun and accessible way?

How to design a new antimicrobial drug?

What structural and dynamical features of molecules make it possible to convert chemical to mechanical energy in both living and nonliving systems?

What is dark matter?

How does culture affect memory and cognition?

How do cells repair broken chromosomes to avoid cancer-causing alterations?

How do sand dunes form?

What are the causes of neurodegenerative diseases like Alzheimer’s, and how do we cure or prevent them?

How can evolution lead to increasing complexity when competition always results in Nash Equilibria?

How do supermassive black holes at the centers of galaxies launch twin jets of plasma that outshine the whole galaxy and travel at faster than 99% of the speed of light?

Why is dimension 4 so special?

How do cells change their gene expression in response to stress?

What can physics and biology learn from each other to make smarter materials and better therapies?

How can we use geometry to identify essential features of abstract groups?

When can you change a complex analytic group action into a linear one?

What will be the next big discovery in particle physics after the HIggs?

How does the mammalian genome build and maintain neuronal circuits?

Are you my substrate?  (How does an enzyme select a particular small molecule substrate out of all the molecules in the cell?)

Can we imbue inanimate materials with features that heretofore are only found in animated matter, such as the beating of a heart at programmable rates and rhythms?

How many are there?

How to target a specific protein for degradation?

How to make an HIV vaccine?

How do chemical reactions change in confined spaces?

Why are some people more stressed than others and how do health behaviors (sleep, exercise) play into this?

What does a random surface look like?

What is the nature of the initial state of the universe, and how did our observed macroscopic spacetime emerge from this?

Why and how do some people age better than others?

Is quantum entanglement the fabric of spacetime?

How do neurons in the brain communicate with one another?

How do we learn to like tastes?

What is the molecular basis of memory storage and what is the biochemical mechanism of its stability?

Can we automate the exploration of big scientific data sets?

How can we best relive our digital past?

Can we provide performance guarantees for cloud databases?